Grace Kanzawa-Lee, Ph.D., BSN, RN
University of Michigan School of Nursing
400 North Ingalls Building
Ann Arbor, MI 48109-5482
Interests
- Cancer survivorship
- Exercise oncology
- Pain and neuropathy
- Interprofessional education and care
Dr. Kanzawa-Lee’s program of research is focused on enhancing patient safety, comfort, and survivorship during active cancer treatment. Her scholarship has centered on multimodal pain & symptom management; exercise therapy to combat the effects of immobility and optimize outcomes during active cancer treatment; and improvement of cancer treatment protocol safety and interprofessional evidence-based care. Her most recent study tested a home-based aerobic walking intervention for chemotherapy-induced peripheral neuropathy in gastrointestinal cancer survivors. The complex intervention included motivational interviewing to facilitate home-based exercise. Dr. Kanzawa-Lee has also collaborated on research focused on innovative and interprofessional educational strategies in classroom and experiential settings.
Current Research Grants and Programs
- Inspiring Growth through Novel Inter-Track Teams of Excellence Program; Co-PI; “Impact of the Self-Determined Evidence-Based Practice Intervention (SD-EBPI) to Promote Clinician Adherence to Evidence-Based Chemotherapy-Induced Peripheral Neuropathy Management”
- Center for Research on Learning and Teaching Foundational Course Initiative; PI; “Foundational Course Initiative Project for Nursing 372: Therapeutic Nursing Care II”
Teaching
Dr. Kanzawa-Lee has taught undergraduate nursing lab, medical surgical clinical, and didactic courses at the UMSN and the graduate nursing course Scientific and Analytic Approaches for Advanced Practice. She has given invited presentations for clinicians at the Infusion Nurses Society, Oncology Nursing Society, and UM Palliative Care conferences. Additionally, she mentored registered nurses in developing manuscripts on their quality improvement projects, graduate students in developing their dissertation theses and lesson plans, and undergraduate and high school students for their Honors/Scholarly projects.
Dr. Kanzawa-Lee strongly believes in the necessity of utilizing multiple teaching methods to help students understand and link concepts, learn to seek additional information, answer the “why” questions, and make informed scientific decisions. She is dedicated to creating an inclusive and engaging learning environment, by encouraging student personal investment, creativity, and collaboration.
Affiliations / Service
- Member, Sigma Theta Tau International Honor Society of Nursing Rho Chapter, 2014-present
- Member & Secretary, Oncology Nursing Society, 2016-present (Putting Evidence in Practice, Peripheral Neuropathy Committee Reviewer 2016-present)
- Member, American College of Sports Medicine, 2016-present
- Member, Multinational Association of Supportive Care in Cancer, 2023-present
Notable Awards / Honors
- IPE Innovation Award, Michigan Center for IPE, 2024
- Rising Star Award, Sigma Theta Tau Rho Chapter, 2020
- Denny Hoelzer Sentinel Technologies Doctoral Scholarship in Cancer Nursing, American Cancer Society, 2018
- New Investigator Award, University of Michigan School of Nursing, 2018
- Hillman Scholarship, Rita and Alex Hillman Foundation, 2013-2017
Education
- Ph.D., University of Michigan, Ann Arbor, MI, 2020
- BSN, University of Michigan, Ann Arbor, MI, 2015
Publication Highlights
Kanzawa-Lee, G.A., Larson, J.L., Resnicow, K., & Smith, E.M.L. (2020). Exercise effects on chemotherapy-induced peripheral neuropathy: A comprehensive integrative review. Cancer Nursing, 43(3), E172-E185. doi: 10.1097/NCC.0000000000000801.
Kanzawa-Lee, G.A., Ploutz-Snyder, R.J., Larson, J.L., Krauss, J.C., Resnicow, K., & Smith, E.M.L. (2022). Efficacy of the Motivational Interviewing-Walk Intervention for chemotherapy-induced peripheral neuropathy and quality of life during oxaliplatin treatment: A pilot randomized controlled trial. Cancer Nursing,45(2), E531-E544. https://doi.org/10.1097/NCC.0000000000001003.
Park, S.B., Tamburin, S., Schenone, A., Kleckner, I.R., Velasco, R., Alberti, P., Kanzawa-Lee, G., Lustberg, M., Dorsey, S.G., Mantovani, E., Hamedani, M., Argyriou, A.A., Cavaletti, G., & Hoke, A., Toxic Neuropathy Consortium. (2022). Optimal outcome measures and methods for studies assessing exercise and physical rehabilitation in chemotherapy-induced peripheral neurotoxicity: A systematic review and consensus expert opinion. Expert Review of Neurotherapeutics,22(1), 65-76. https://doi.org/10.1080/14737175.2022.2018300.
Kanzawa-Lee, G.A., Krauss, J.C., & Knoerl, R. (2024). Exploring chemotherapy-induced peripheral neuropathy management practice patterns among oncology clinicians. Seminars in Oncology Nursing, 40(5), 151685. https://doi.org/10.1016/j.soncn.2024.151685.
Kanzawa-Lee, G.A., Larson, J.L., Resnicow, K., Ploutz-Snyder, R., Krauss, J.C., & Smith, E.M.L. (2024). Home-based aerobic exercise feasibility in oxaliplatin-receiving newly-diagnosed cancer survivors. European Journal of Oncology Nursing, 71,102649. https://doi.org/10.1016/j.ejon.2024.102649.
Smith, E.M.L., Kuisell, C., Kanzawa-Lee, G., Bridges, C.M., Cho, Y., Swets, J., Gilchrist, L.S. (2021). Assessment of pediatric chemotherapy-induced peripheral neuropathy (CIPN) using a new patient-reported outcome measure: The P-CIN. Journal of Pediatric Oncology Nursing, 38(2), 131-141. https://doi.org/10.1177/1043454220980253.
Smith, E.M., Bridges, C.M., Kanzawa, G., Knoerl, R., Kelly, J.P., Berezvosky, A., & Woo, C. (2014). Cancer treatment-related neuropathic pain syndromes—Epidemiology and treatment: An update. Current Pain and Headache Reports, 18(11), 459. doi:10.1007/s11916-014-0459-7.
Smith, E.M.L., Knoerl, R., Yang, J., Kanzawa-Lee, G., & Bridges, C. (2018). In search of a gold standard patient-reported outcome measure for use in chemotherapy-induced peripheral neuropathy clinical trials. Cancer Control, 25(1). doi: 10.1177/1073274818756608.
Kanzawa-Lee, G., Harte, S.E., Bridges, C.M., Brummett, C., Clauw, D.J., Williams, D.A., Knoerl, R., & Smith, E.M.L. (2018). Pressure pain phenotypes in women before breast cancer treatment. Oncology Nursing Forum, 45(4), 483-495. doi: 10.1188/18.ONF.483-495.
Kanzawa-Lee, G., Knoerl, R., Williams, D.A., Clauw, D.J., Bridges, C. M., Harte, S.E., Kolarik, E., Houghtby, J., & Smith, E.M.L. (2018). Childhood trauma predicts cancer treatment-related pain in breast cancer survivors. Cancer Nursing, 43(4), E207-E216. doi: 10.1097/NCC.0000000000000687.
Smith, E.M.L., Zanville, N., Kanzawa-Lee, G., Donohoe, C., Bridges, C., Loprinzi, C.,…, Yang, J.J. (2018). Rasch model-based testing of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy (QLQ-CIPN20) using Alliance for Clinical Trials in Oncology (Alliance) A151408 study data. Supportive Care in Cancer, 27(7), 2599-2608. doi: 10.1007/s00520-018-4553-y.
Lee, D., Kanzawa-Lee, G., Knoerl, R., Wyatt, G., Smith, E.M.L. (2019). Characterization of internal validity threats to phase III clinical trials for chemotherapy-induced peripheral neuropathy management: A systematic review. APJON, 46(2). doi: 10.4103/apjon.apjon_14_19.
Kanzawa-Lee, G.A., Donohoe, C., Knoerl, R., Bridges, C.M., Smith, E.M.L. (2019). Mechanisms, predictors, and challenges in assessing and managing painful chemotherapy-induced peripheral neuropathy. Seminars in Oncology Nursing, 35(3), 253-260. doi: 10.1016/j.soncn.2019.04.006.
Kanzawa-Lee, G. (2020). Chemotherapy-induced peripheral neuropathy: Nursing implications. Journal of Infusion Nursing: The official publication of the Infusion Nurses Society, 43(3), 155-156. doi:10.1097/NAN.0000000000000368.
Smith, E.M.L, Donohoe, C., Kanzawa-Lee, G.A., Alberti, P., Cavaletti, G., Saad, R., Bridges, C.B., Park, S., the Toxic Neuropathy Consortium of the Peripheral Nerve Society. (2020). Approaches to measure paediatric chemotherapy-induced peripheral neurotoxicity: A systematic review. Lancet Haematology, 7(5), e408-e417. doi: 10.1016/S2352-3026(20)30064-8.
