Yuh-Pey Anne Buu, PhD (Stats), PhD (Ed. Psych)

Associate Professor
Department of Health Behavior and Biological Sciences
Room 4346 400NIB

University of Michigan School of Nursing
400 North Ingalls Building
Ann Arbor, MI 48109-5482

Telephone: (734) 764-9008
Fax: (734) 647-2416

Scholarly Expertise / Activity


  • Longitudinal data analysis
  • Bioinformatics
  • Health communication
  • Substance abuse prevention
  • Developmental psychology

 Dr. Buu is a biostatistician and developmental psychologist. Her research interests include longitudinal data analysis, bioinformatics, health communication, substance abuse prevention, and developmental psychology. She is the recipient of a Research Scientist Development Award from the National Institute on Alcohol Abuse and Alcoholism and has been the Principal Investigator of two five-year methodology projects funded by the National Institutes of Health (NIH). She has also served as a study statistician for several longitudinal projects funded by the NIH such as the Michigan Longitudinal Study and the Flint Adolescent Study. She has published in statistical journals (such as the Journal of the Royal Statistical Society; Statistics in Medicine; and Bioinformatics) as well as in psychological journals (including Journal of Abnormal Psychology; and Development and Psychopathology). She has also published in substance abuse journals such as Addiction; and Drug and Alcohol Dependence.

Current Research Grants and Programs:

  • Measurement and Methodology for Daily Patterns of Drug Use and Related Behaviors: NIH/NIDA (R01DA035183) (Role: Principal investigator).
  • Intergenerational Transmission of Drug Use in an Urban Sample: NIH/NIDA (R01DA035811) (Role: Co-investigator)
  • Measuring Approaches to Partnership Success (MAPS): NIH/NINR (R01 NR016123). (Role: Co-investigator)


Dr. Buu has taught statistics courses at the University of North Carolina-Chapel Hill, the University of Michigan-Ann Arbor, and the Indiana University-Bloomington. She has taught introductory statistics at both the undergraduate and graduate levels. She has also taught a graduate level multivariate statistics course. She loves to engage students in class through group activities and paper presentations. She specializes in teaching students in behavioral science and health science for whom the practical contexts and applications are more important than technical or computational details. Her teaching emphasizes the training of students’ ability to carry out statistical analysis using software and interpret results accurately. She teaches HS 550 Scientific Methods for Health Sciences: Fundamentals which is a master's level course open to graduate students in all health science schools.

Affiliations / Service

  • Member, American Statistical Association, 2001-present
  • Member, Research Society on Alcoholism, 2005-present
  • Member, American Psychological Association, 2012-present
  • Member, Institute of Mathematical Statistics, 2015-present

Notable Awards / Honors

  • Research Scientist Development Award, National Institutes of Health, 2009
  • Fu Si-Nian Scholarship, National Taiwan University, 1991


  • Ph.D. in Statistics, University of Florida, Gainesville, FL 2003
  • Ph.D. in Educational Psychology, Indiana University, Bloomington, IN 1999

Publication Highlights

  • Buu, A., Williams, L.K., & Yang, J.J. (in press). An efficient genome-wide association test for mixed binary and continuous phenotypes with applications to substance abuse research. Statistical Methods in Medical Research.
  • Yang, J.J., Li, J., Williams, L.K. & Buu, A. (2016). An efficient genome-wide association test for multivariate phenotypes based on the Fisher combination function. BMC Bioinformatics, 17:19. doi: 10.1186/s12859-015-0868-6.
  • Yang, H., Li, R., Zucker, R.A., & Buu, A. (2016). Two-stage model for time-varying effects of zero-inflated count longitudinal covariates with applications in health behavior research. Journal of the Royal Statistical Society: Series C, 65, 431-444.
  • Arterberry, B., Horbal, S.R., Buu, A., & Lin, H. (2016). The effects of alcohol, cannabis, and cigarette use on the initiation, reinitiation and persistence of non-medical use of opioids, sedatives, and tranquilizers in adults. Drug and Alcohol Dependence, 159, 86-92.
  • Buu, A., Dabrowska, A., Heinze, J.E., Hsieh, H., & Zimmerman, M.A. (2015). Gender differences in the developmental trajectories of multiple substance use and the effect of nicotine and marijuana use on heavy drinking in a high risk sample. Addictive Behaviors, 50, 6-12.
  • Jester, J.M., Wong, M.M., Cranford, J.A., Buu, A., Fitzgerald, H.E., & Zucker, R.A. (2015). Alcohol expectancies in childhood: change with the onset of drinking and ability to predict adolescent drunkenness and binge drinking. Addiction, 110, 71-79.
  • Yang, H., Cranford, J.A., Li, R., & Buu, A. (2015). Two-stage model for time-varying effects of discrete longitudinal covariates with applications in analysis of daily process data. Statistics in Medicine, 34, 571-581.
  • Dziak, J.J., Li, R., Zimmerman, M.A., & Buu, A. (2014). Time-varying effect models for ordinal responses with applications in substance abuse research. Statistics in Medicine, 33, 5126-5137.
  • Yang, J.J., Li, J., Buu, A., & Williams, L.K. (2013). Efficient inference of local ancestry. Bioinformatics, 29, 2750-2756.
  • Buu, A., Wang, W., Schroder, S.A., Kalaida, N.L., Puttler, L.I., & Zucker, R.A. (2012). Developmental emergence of alcohol use disorder symptoms and their potential as early indicators for progression to alcohol dependence in a high risk sample: a longitudinal study from childhood to early adulthood. Journal of Abnormal Psychology, 121, 897-908.
  • Buu, A., Johnson, N.J., Li, R., & Tan, X. (2011). New variable selection methods for zero-inflated count data with applications to the substance abuse field. Statistics in Medicine, 30, 2326-2340.
  • Buu, A., Wang, W., Wang, J., Puttler, L.I., Fitzgerald, H.E., & Zucker, R.A. (2011). Changes in women’s alcoholic, antisocial, and depressive symptomatology over 12 years: a multilevel network of individual, familial, and neighborhood influences. Development and Psychopathology, 23, 325-337.
  • Buu, A., DiPiazza, C., Wang, J., Puttler, L.I., Fitzgerald, H.E., & Zucker, R.A. (2009). Parent, family, and neighborhood effects on the development of child substance use and other psychopathology from preschool to the start of adulthood. Journal of Studies on Alcohol and Drugs, 70, 489-498.
  • Glass, J.M., Buu, A., Adams, K.M., Nigg, J.T., Puttler, L.I., Jester, J.M.,& Zucker, R.A. (2009). Effects of alcoholism severity and smoking on executive neurocognitive function. Addiction, 104, 38-48.
  • Buu, A., Mansour, M., Wang, J., Refior, S.K., Fitzgerald, H.E., & Zucker, R.A. (2007). Alcoholism effects on social migration and neighborhood effects on alcoholism over the course of 12 years. Alcoholism: Clinical and Experimental Research, 31, 1545-1551.